FTO demethylase activity is essential for normal bone growth and bone mineralization in mice

The Fto gene locus has been linked to increased body weight and obesity in human population studies, but the role of the actual FTO protein in adiposity has remained controversial. Complete loss of FTO protein in mouse and of FTO function in human patients has multiple and variable effects. To deter...

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Detalles Bibliográficos
Autores principales: Sachse, Gregor, Church, Chris, Stewart, Michelle, Cater, Heather, Teboul, Lydia, Cox, Roger D., Ashcroft, Frances M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798602/
https://www.ncbi.nlm.nih.gov/pubmed/29203346
http://dx.doi.org/10.1016/j.bbadis.2017.11.027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798602/
https://www.ncbi.nlm.nih.gov/pubmed/29203346
http://dx.doi.org/10.1016/j.bbadis.2017.11.027

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