Protective role of FKBP51 in calcium entry-induced endothelial barrier disruption

Pulmonary artery endothelial cells (PAECs) express a cation current, I(SOC) (store-operated calcium entry current), which when activated permits calcium entry leading to inter-endothelial cell gap formation. The large molecular weight immunophilin FKBP51 inhibits I(SOC) but not other calcium entry p...

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Detalles Bibliográficos
Autores principales: Hamilton, Caleb L., Kadeba, Pierre I., Vasauskas, Audrey A., Solodushko, Viktoriya, McClinton, Anna K., Alexeyev, Mikhail, Scammell, Jonathan G., Cioffi, Donna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798693/
https://www.ncbi.nlm.nih.gov/pubmed/29261039
http://dx.doi.org/10.1177/2045893217749987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798693/
https://www.ncbi.nlm.nih.gov/pubmed/29261039
http://dx.doi.org/10.1177/2045893217749987

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