Synthesis, stabilization, and characterization of the MR1 ligand precursor 5-amino-6-D-ribitylaminouracil (5-A-RU)

Mucosal-associated invariant T (MAIT) cells are an abundant class of innate T cells restricted by the MHC I-related molecule MR1. MAIT cells can recognize bacterially-derived metabolic intermediates from the riboflavin pathway presented by MR1 and are postulated to play a role in innate antibacteria...

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Detalles Bibliográficos
Autores principales: Li, Kelin, Vorkas, Charles K., Chaudhry, Ashutosh, Bell, Donielle L., Willis, Richard A., Rudensky, Alexander, Altman, John D., Glickman, Michael S., Aubé, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798775/
https://www.ncbi.nlm.nih.gov/pubmed/29401462
http://dx.doi.org/10.1371/journal.pone.0191837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798775/
https://www.ncbi.nlm.nih.gov/pubmed/29401462
http://dx.doi.org/10.1371/journal.pone.0191837

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