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Quantitative and histological assessment of maternal-fetal transmission of Trypanosoma cruzi in guinea pigs: An experimental model of congenital Chagas disease

OBJECTIVE: We evaluated the effect of Trypanosoma cruzi infection on fertility, gestation outcome, and maternal-fetal transmission in guinea pigs (Cavia porcellus). METHODS: Animals were infected with T. cruzi H4 strain (TcI lineage) before gestation (IBG) or during gestation (IDG). Tissue and sera...

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Detalles Bibliográficos
Autores principales: Torres-Vargas, Jatziri, Jiménez-Coello, Matilde, Guzmán-Marín, Eugenia, Acosta-Viana, Karla Y., Yadon, Zaida E., Gutiérrez-Blanco, Eduardo, Guillermo-Cordero, José Leonardo, Garg, Nisha J., Ortega-Pacheco, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798842/
https://www.ncbi.nlm.nih.gov/pubmed/29364882
http://dx.doi.org/10.1371/journal.pntd.0006222