Sequence determinants of protein phase behavior from a coarse-grained model

Membraneless organelles important to intracellular compartmentalization have recently been shown to comprise assemblies of proteins which undergo liquid-liquid phase separation (LLPS). However, many proteins involved in this phase separation are at least partially disordered. The molecular mechanism...

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Detalles Bibliográficos
Autores principales: Dignon, Gregory L., Zheng, Wenwei, Kim, Young C., Best, Robert B., Mittal, Jeetain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798848/
https://www.ncbi.nlm.nih.gov/pubmed/29364893
http://dx.doi.org/10.1371/journal.pcbi.1005941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798848/
https://www.ncbi.nlm.nih.gov/pubmed/29364893
http://dx.doi.org/10.1371/journal.pcbi.1005941

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