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Sequence determinants of protein phase behavior from a coarse-grained model
Membraneless organelles important to intracellular compartmentalization have recently been shown to comprise assemblies of proteins which undergo liquid-liquid phase separation (LLPS). However, many proteins involved in this phase separation are at least partially disordered. The molecular mechanism...
Autores principales: | Dignon, Gregory L., Zheng, Wenwei, Kim, Young C., Best, Robert B., Mittal, Jeetain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798848/ https://www.ncbi.nlm.nih.gov/pubmed/29364893 http://dx.doi.org/10.1371/journal.pcbi.1005941 |
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