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The structure of FIV reverse transcriptase and its implications for non-nucleoside inhibitor resistance
Reverse transcriptase (RT) is the target for the majority of anti-HIV-1 drugs. As with all anti-AIDS treatments, continued success of RT inhibitors is persistently disrupted by the occurrence of resistance mutations. To explore latent resistance mechanisms potentially accessible to therapeutically c...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798851/ https://www.ncbi.nlm.nih.gov/pubmed/29364950 http://dx.doi.org/10.1371/journal.ppat.1006849 |