TUFT1 interacts with RABGAP1 and regulates mTORC1 signaling

The mammalian target of rapamycin (mTOR) pathway is commonly activated in human cancers. The activity of mTOR complex 1 (mTORC1) signaling is supported by the intracellular positioning of cellular compartments and vesicle trafficking, regulated by Rab GTPases. Here we showed that tuftelin 1 (TUFT1)...

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Detalles Bibliográficos
Autores principales: Kawasaki, Natsumi, Isogaya, Kazunobu, Dan, Shingo, Yamori, Takao, Takano, Hiroshi, Yao, Ryoji, Morishita, Yasuyuki, Taguchi, Luna, Morikawa, Masato, Heldin, Carl-Henrik, Noda, Tetsuo, Ehata, Shogo, Miyazono, Kohei, Koinuma, Daizo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798889/
https://www.ncbi.nlm.nih.gov/pubmed/29423269
http://dx.doi.org/10.1038/s41421-017-0001-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798889/
https://www.ncbi.nlm.nih.gov/pubmed/29423269
http://dx.doi.org/10.1038/s41421-017-0001-2

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