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TUFT1 interacts with RABGAP1 and regulates mTORC1 signaling

The mammalian target of rapamycin (mTOR) pathway is commonly activated in human cancers. The activity of mTOR complex 1 (mTORC1) signaling is supported by the intracellular positioning of cellular compartments and vesicle trafficking, regulated by Rab GTPases. Here we showed that tuftelin 1 (TUFT1)...

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Detalles Bibliográficos
Autores principales:	Kawasaki, Natsumi, Isogaya, Kazunobu, Dan, Shingo, Yamori, Takao, Takano, Hiroshi, Yao, Ryoji, Morishita, Yasuyuki, Taguchi, Luna, Morikawa, Masato, Heldin, Carl-Henrik, Noda, Tetsuo, Ehata, Shogo, Miyazono, Kohei, Koinuma, Daizo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798889/ https://www.ncbi.nlm.nih.gov/pubmed/29423269 http://dx.doi.org/10.1038/s41421-017-0001-2

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