The FGFR4-388arg Variant Promotes Lung Cancer Progression by N-Cadherin Induction

The FGFR4-388Arg variant has been related to poor prognosis in several types of cancer, including lung cancer. The mechanism underlying this association has not been addressed in detail in patients with this pathology. Here, we report that this FGFR4 variant induces MAPK and STAT3 activation and cau...

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Detalles Bibliográficos
Autores principales: Quintanal-Villalonga, Álvaro, Ojeda-Márquez, Laura, Marrugal, Ángela, Yagüe, Patricia, Ponce-Aix, Santiago, Salinas, Ana, Carnero, Amancio, Ferrer, Irene, Molina-Pinelo, Sonia, Paz-Ares, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799167/
https://www.ncbi.nlm.nih.gov/pubmed/29402970
http://dx.doi.org/10.1038/s41598-018-20570-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799167/
https://www.ncbi.nlm.nih.gov/pubmed/29402970
http://dx.doi.org/10.1038/s41598-018-20570-3

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