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The FGFR4-388arg Variant Promotes Lung Cancer Progression by N-Cadherin Induction
The FGFR4-388Arg variant has been related to poor prognosis in several types of cancer, including lung cancer. The mechanism underlying this association has not been addressed in detail in patients with this pathology. Here, we report that this FGFR4 variant induces MAPK and STAT3 activation and cau...
Autores principales: | Quintanal-Villalonga, Álvaro, Ojeda-Márquez, Laura, Marrugal, Ángela, Yagüe, Patricia, Ponce-Aix, Santiago, Salinas, Ana, Carnero, Amancio, Ferrer, Irene, Molina-Pinelo, Sonia, Paz-Ares, Luis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799167/ https://www.ncbi.nlm.nih.gov/pubmed/29402970 http://dx.doi.org/10.1038/s41598-018-20570-3 |
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