ITGB1-dependent upregulation of Caveolin-1 switches TGFβ signalling from tumour-suppressive to oncogenic in prostate cancer

Caveolin-1 (CAV1) is over-expressed in prostate cancer (PCa) and is associated with adverse prognosis, but the molecular mechanisms linking CAV1 expression to disease progression are poorly understood. Extensive gene expression correlation analysis, quantitative multiplex imaging of clinical samples...

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Detalles Bibliográficos
Autores principales: Pellinen, Teijo, Blom, Sami, Sánchez, Sara, Välimäki, Katja, Mpindi, John-Patrick, Azegrouz, Hind, Strippoli, Raffaele, Nieto, Raquel, Vitón, Mariano, Palacios, Irene, Turkki, Riku, Wang, Yinhai, Sánchez-Alvarez, Miguel, Nordling, Stig, Bützow, Anna, Mirtti, Tuomas, Rannikko, Antti, Montoya, María C., Kallioniemi, Olli, del Pozo, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799174/
https://www.ncbi.nlm.nih.gov/pubmed/29402961
http://dx.doi.org/10.1038/s41598-018-20161-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799174/
https://www.ncbi.nlm.nih.gov/pubmed/29402961
http://dx.doi.org/10.1038/s41598-018-20161-2

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