Gs- versus Golf-dependent functional selectivity mediated by the dopamine D(1) receptor

The two highly homologous subtypes of stimulatory G proteins Gαs (Gs) and Gαolf (Golf) display contrasting expression patterns in the brain. Golf is predominant in the striatum, while Gs is predominant in the cortex. Yet, little is known about their functional distinctions. The dopamine D(1) recepto...

Descripción completa

Detalles Bibliográficos
Autores principales: Yano, Hideaki, Cai, Ning-Sheng, Xu, Min, Verma, Ravi Kumar, Rea, William, Hoffman, Alexander F., Shi, Lei, Javitch, Jonathan A., Bonci, Antonello, Ferré, Sergi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799184/
https://www.ncbi.nlm.nih.gov/pubmed/29402888
http://dx.doi.org/10.1038/s41467-017-02606-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799184/
https://www.ncbi.nlm.nih.gov/pubmed/29402888
http://dx.doi.org/10.1038/s41467-017-02606-w

Ejemplares similares