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Gs- versus Golf-dependent functional selectivity mediated by the dopamine D(1) receptor
The two highly homologous subtypes of stimulatory G proteins Gαs (Gs) and Gαolf (Golf) display contrasting expression patterns in the brain. Golf is predominant in the striatum, while Gs is predominant in the cortex. Yet, little is known about their functional distinctions. The dopamine D(1) recepto...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799184/ https://www.ncbi.nlm.nih.gov/pubmed/29402888 http://dx.doi.org/10.1038/s41467-017-02606-w |