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Conformation of methylated GGQ in the Peptidyl Transferase Center during Translation Termination

The universally conserved Gly-Gly-Gln (GGQ) tripeptide in release factors or release factor-like surveillance proteins is required to catalyze the release of nascent peptide in the ribosome. The glutamine of the GGQ is methylated post-translationally at the N(5) position in vivo; this covalent modif...

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Detalles Bibliográficos
Autores principales: Zeng, Fuxing, Jin, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799190/
https://www.ncbi.nlm.nih.gov/pubmed/29403017
http://dx.doi.org/10.1038/s41598-018-20107-8