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Insights into the Structural Basis of Antibody Affinity Maturation from Next-Generation Sequencing
Affinity maturation is the process whereby the immune system generates antibodies of higher affinities during a response to antigen. It is unique in being the only evolutionary mechanism known to operate on a molecule in an organism’s own body. Deciphering the structural mechanisms through which som...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799246/ https://www.ncbi.nlm.nih.gov/pubmed/29449843 http://dx.doi.org/10.3389/fimmu.2018.00117 |