Cargando…
Insights into the Structural Basis of Antibody Affinity Maturation from Next-Generation Sequencing
Affinity maturation is the process whereby the immune system generates antibodies of higher affinities during a response to antigen. It is unique in being the only evolutionary mechanism known to operate on a molecule in an organism’s own body. Deciphering the structural mechanisms through which som...
Autores principales: | Mishra, Arjun K., Mariuzza, Roy A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799246/ https://www.ncbi.nlm.nih.gov/pubmed/29449843 http://dx.doi.org/10.3389/fimmu.2018.00117 |
Ejemplares similares
-
Structural Basis for Recognition of Cellular and Viral Ligands by NK Cell Receptors
por: Li, Yili, et al.
Publicado: (2014) -
Structural basis for T cell recognition of cancer neoantigens and implications for predicting neoepitope immunogenicity
por: Mariuzza, Roy A., et al.
Publicado: (2023) -
Structural and Biophysical Insights into the Role of CD4 and CD8 in T Cell Activation
por: Li, Yili, et al.
Publicado: (2013) -
Next-Generation Sequencing of Antibody Display Repertoires
por: Rouet, Romain, et al.
Publicado: (2018) -
The Application of Next Generation Sequencing to the Understanding of Antibody Repertoires
por: Mathonet, Pascale, et al.
Publicado: (2013)