Genetic variability affects absolute and relative potencies and kinetics of the anesthetics isoflurane and sevoflurane in Drosophila melanogaster

Genetic variability affects the response to numerous xenobiotics but its role in the clinically-observed irregular responses to general anesthetics remains uncertain. To investigate the pharmacogenetics of volatile general anesthetics (VGAs), we developed a Serial Anesthesia Array apparatus to expos...

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Detalles Bibliográficos
Autores principales: Olufs, Zachariah P. G., Loewen, Carin A., Ganetzky, Barry, Wassarman, David A., Perouansky, Misha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799260/
https://www.ncbi.nlm.nih.gov/pubmed/29402974
http://dx.doi.org/10.1038/s41598-018-20720-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799260/
https://www.ncbi.nlm.nih.gov/pubmed/29402974
http://dx.doi.org/10.1038/s41598-018-20720-7

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