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A Critical Examination of Subgroup Analyses: The National Acute Spinal Cord Injury Studies and Beyond

The use of high-dose methylprednisolone for acute spinal cord injury continues to be a topic of debate. This controversy largely stems from fundamental issues in statistical interpretation of trial data, most notably subgroup analyses. The purpose of this review is to discuss important examples of i...

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Detalles Bibliográficos
Autores principales: Hextrum, Shannon, Bennett, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799288/
https://www.ncbi.nlm.nih.gov/pubmed/29449826
http://dx.doi.org/10.3389/fneur.2018.00011