Neuroprotective effects of pifithrin-α against traumatic brain injury in the striatum through suppression of neuroinflammation, oxidative stress, autophagy, and apoptosis

Cortical and hippocampal neuronal damages caused by traumatic brain injury (TBI) are associated with motor and cognitive impairments; however, only little attention paid to the striatal damage. It is known that the p53 tumor-suppressor transcription factor participated in TBI-induced secondary brain...

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Detalles Bibliográficos
Autores principales: Huang, Ya-Ni, Yang, Ling-Yu, Greig, Nigel H., Wang, Yu-Chio, Lai, Chien-Cheng, Wang, Jia-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799311/
https://www.ncbi.nlm.nih.gov/pubmed/29402897
http://dx.doi.org/10.1038/s41598-018-19654-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799311/
https://www.ncbi.nlm.nih.gov/pubmed/29402897
http://dx.doi.org/10.1038/s41598-018-19654-x

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