Selective Inhibition of Succinate Dehydrogenase in Reperfused Myocardium with Intracoronary Malonate Reduces Infarct Size

Inhibition of succinate dehydrogenase (SDH) with malonate during reperfusion reduces infarct size in isolated mice hearts submitted to global ischemia. However, malonate has toxic effects that preclude its systemic administration in animals. Here we investigated the effect of intracoronary malonate...

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Detalles Bibliográficos
Autores principales: Valls-Lacalle, Laura, Barba, Ignasi, Miró-Casas, Elisabet, Ruiz-Meana, Marisol, Rodríguez-Sinovas, Antonio, García-Dorado, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799359/
https://www.ncbi.nlm.nih.gov/pubmed/29402957
http://dx.doi.org/10.1038/s41598-018-20866-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799359/
https://www.ncbi.nlm.nih.gov/pubmed/29402957
http://dx.doi.org/10.1038/s41598-018-20866-4

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