Regulation of chitinase-3-like-1 in T cell elicits Th1 and cytotoxic responses to inhibit lung metastasis

Chitinase-3-like-1 (Chi3l1) is known to play a significant role in the pathogenesis of Type 2 inflammation and cancer. However, the function of Chi3l1 in T cell and its clinical implications are largely unknown. Here we show that Chi3l1 expression was increased in activated T cells, especially in Th...

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Detalles Bibliográficos
Autores principales: Kim, Do-Hyun, Park, Hong-Jai, Lim, Sangho, Koo, Ja-Hyun, Lee, Hong-Gyun, Choi, Jin Ouk, Oh, Ji Hoon, Ha, Sang-Jun, Kang, Min-Jong, Lee, Chang-Min, Lee, Chun Geun, Elias, Jack A., Choi, Je-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799380/
https://www.ncbi.nlm.nih.gov/pubmed/29403003
http://dx.doi.org/10.1038/s41467-017-02731-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799380/
https://www.ncbi.nlm.nih.gov/pubmed/29403003
http://dx.doi.org/10.1038/s41467-017-02731-6

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