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Regulation of chitinase-3-like-1 in T cell elicits Th1 and cytotoxic responses to inhibit lung metastasis
Chitinase-3-like-1 (Chi3l1) is known to play a significant role in the pathogenesis of Type 2 inflammation and cancer. However, the function of Chi3l1 in T cell and its clinical implications are largely unknown. Here we show that Chi3l1 expression was increased in activated T cells, especially in Th...
Autores principales: | Kim, Do-Hyun, Park, Hong-Jai, Lim, Sangho, Koo, Ja-Hyun, Lee, Hong-Gyun, Choi, Jin Ouk, Oh, Ji Hoon, Ha, Sang-Jun, Kang, Min-Jong, Lee, Chang-Min, Lee, Chun Geun, Elias, Jack A., Choi, Je-Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799380/ https://www.ncbi.nlm.nih.gov/pubmed/29403003 http://dx.doi.org/10.1038/s41467-017-02731-6 |
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