Oncogenic RAS-induced CK1α drives nuclear FOXO proteolysis

Evasion of forkhead box O (FOXO) family of longevity-related transcription factors-mediated growth suppression is necessary to promote cancer development. Since somatic alterations or mutations and transcriptional dysregulation of the FOXO genes are infrequent in human cancers, it remains unclear ho...

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Detalles Bibliográficos
Autores principales: Zhang, F, Virshup, D M, Cheong, J K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799771/
https://www.ncbi.nlm.nih.gov/pubmed/28945225
http://dx.doi.org/10.1038/onc.2017.334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799771/
https://www.ncbi.nlm.nih.gov/pubmed/28945225
http://dx.doi.org/10.1038/onc.2017.334

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