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Oncogenic RAS-induced CK1α drives nuclear FOXO proteolysis

Evasion of forkhead box O (FOXO) family of longevity-related transcription factors-mediated growth suppression is necessary to promote cancer development. Since somatic alterations or mutations and transcriptional dysregulation of the FOXO genes are infrequent in human cancers, it remains unclear ho...

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Detalles Bibliográficos
Autores principales:	Zhang, F, Virshup, D M, Cheong, J K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799771/ https://www.ncbi.nlm.nih.gov/pubmed/28945225 http://dx.doi.org/10.1038/onc.2017.334

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