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ING5 activity in self-renewal of glioblastoma stem cells via calcium and follicle stimulating hormone pathways

Stem cell-like brain tumor initiating cells (BTICs) cause recurrence of glioblastomas, with BTIC ‘stemness’ affected by epigenetic mechanisms. The ING family of epigenetic regulators (ING1-5) function by targeting histone acetyltransferase (HAT) or histone deacetylase complexes to the H3K4me3 mark t...

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Detalles Bibliográficos
Autores principales: Wang, F, Wang, A Y, Chesnelong, C, Yang, Y, Nabbi, A, Thalappilly, S, Alekseev, V, Riabowol, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799773/
https://www.ncbi.nlm.nih.gov/pubmed/28925404
http://dx.doi.org/10.1038/onc.2017.324