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Rab25 augments cancer cell invasiveness through a β1 integrin/EGFR/VEGF-A/Snail signaling axis and expression of fascin

The small GTP-binding protein Rab25 is associated with tumor formation and progression. However, recent studies have shown discordant effects of Rab25 on cancer cell progression depending on cell lineage. In the present study, we elucidate the underlying mechanisms by which Rab25 induces cellular in...

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Detalles Bibliográficos
Autores principales: Jeong, Bo Young, Cho, Kyung Hwa, Jeong, Kang Jin, Park, Yun-Yong, Kim, Jin Man, Rha, Sun Young, Park, Chang Gyo, Mills, Gordon B, Cheong, Jae-Ho, Lee, Hoi Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799805/
https://www.ncbi.nlm.nih.gov/pubmed/29371698
http://dx.doi.org/10.1038/emm.2017.248