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PIK3CA and TP53 mutations predict overall survival of stage II/III colorectal cancer patients

AIM: To investigate the predictive value of PIK3CA and TP53 mutation status in colorectal cancer (CRC) patients treated with 5-fluorouracil-based chemotherapy. METHODS: In this study, a total of 315 patients with histologically proven CRC were enrolled from Yangpu Hospital affiliated to Shanghai Ton...

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Detalles Bibliográficos
Autores principales: Li, A-Jian, Li, Hua-Guang, Tang, Er-Jiang, Wu, Wei, Chen, Ying, Jiang, Hui-Hong, Lin, Mou-Bin, Yin, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799864/
https://www.ncbi.nlm.nih.gov/pubmed/29434452
http://dx.doi.org/10.3748/wjg.v24.i5.631