Cargando…
Two-Step Macrocycle Synthesis by Classical Ugi Reaction
[Image: see text] The direct nonpeptidic macrocycle synthesis of α-isocyano-ω-amines via the classical Ugi four-component reaction (U-4CR) is introduced. Herein an efficient and flexible two-step procedure to complex macrocycles is reported. In the first step, the reaction between unprotected diamin...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2018
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799868/ https://www.ncbi.nlm.nih.gov/pubmed/29327924 http://dx.doi.org/10.1021/acs.joc.7b02984 |