Cargando…
Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation
[Image: see text] Chemical modification of proteins is essential for a variety of important diagnostic and therapeutic applications. Many strategies developed to date lack chemo- and regioselectivity as well as result in non-native linkages that may suffer from instability in vivo and adversely affe...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2017
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799870/ https://www.ncbi.nlm.nih.gov/pubmed/29206031 http://dx.doi.org/10.1021/jacs.7b10702 |