Chemoselective Installation of Amine Bonds on Proteins through Aza-Michael Ligation

[Image: see text] Chemical modification of proteins is essential for a variety of important diagnostic and therapeutic applications. Many strategies developed to date lack chemo- and regioselectivity as well as result in non-native linkages that may suffer from instability in vivo and adversely affe...

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Detalles Bibliográficos
Autores principales: Freedy, Allyson M., Matos, Maria J., Boutureira, Omar, Corzana, Francisco, Guerreiro, Ana, Akkapeddi, Padma, Somovilla, Víctor J., Rodrigues, Tiago, Nicholls, Karl, Xie, Bangwen, Jiménez-Osés, Gonzalo, Brindle, Kevin M., Neves, André A., Bernardes, Gonçalo J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799870/
https://www.ncbi.nlm.nih.gov/pubmed/29206031
http://dx.doi.org/10.1021/jacs.7b10702

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