Systematic prediction of DNA shape changes due to CpG methylation explains epigenetic effects on protein–DNA binding

BACKGROUND: DNA shape analysis has demonstrated the potential to reveal structure-based mechanisms of protein–DNA binding. However, information about the influence of chemical modification of DNA is limited. Cytosine methylation, the most frequent modification, represents the addition of a methyl gr...

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Detalles Bibliográficos
Autores principales: Rao, Satyanarayan, Chiu, Tsu-Pei, Kribelbauer, Judith F., Mann, Richard S., Bussemaker, Harmen J., Rohs, Remo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800008/
https://www.ncbi.nlm.nih.gov/pubmed/29409522
http://dx.doi.org/10.1186/s13072-018-0174-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800008/
https://www.ncbi.nlm.nih.gov/pubmed/29409522
http://dx.doi.org/10.1186/s13072-018-0174-4

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