Cargando…
Systematic prediction of DNA shape changes due to CpG methylation explains epigenetic effects on protein–DNA binding
BACKGROUND: DNA shape analysis has demonstrated the potential to reveal structure-based mechanisms of protein–DNA binding. However, information about the influence of chemical modification of DNA is limited. Cytosine methylation, the most frequent modification, represents the addition of a methyl gr...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800008/ https://www.ncbi.nlm.nih.gov/pubmed/29409522 http://dx.doi.org/10.1186/s13072-018-0174-4 |