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MORG1(+/−) mice are protected from histological renal damage and inflammation in a murine model of endotoxemia

BACKGROUND: The MAPK-organizer 1 (MORG1) play a scaffold function in the MAPK and/or the PHD3 signalling paths. Recently, we reported that MORG1(+/−) mice are protected from renal injury induced by systemic hypoxia and acute renal ischemia-reperfusion injury via increased hypoxia-inducible factors (...

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Detalles Bibliográficos
Autores principales: Bondeva, Tzvetanka, Schindler, Claudia, Schindler, Katrin, Wolf, Gunter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800025/
https://www.ncbi.nlm.nih.gov/pubmed/29402223
http://dx.doi.org/10.1186/s12882-018-0826-4