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Hepatic stem cells with self-renewal and liver repopulation potential are harbored in CDCP1-positive subpopulations of human fetal liver cells

BACKGROUND: Mature human hepatocytes are critical in preclinical research and therapy for liver disease, but are difficult to manipulate and expand in vitro. Hepatic stem cells (HpSCs) may be an alternative source of functional hepatocytes for cell therapy and disease modeling. Since these cells pla...

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Detalles Bibliográficos
Autores principales: Zhang, Ran-Ran, Zheng, Yun-Wen, Li, Bin, Nie, Yun-Zhong, Ueno, Yasuharu, Tsuchida, Tomonori, Taniguchi, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800061/
https://www.ncbi.nlm.nih.gov/pubmed/29402311
http://dx.doi.org/10.1186/s13287-017-0747-3