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Pervasive Correlated Evolution in Gene Expression Shapes Cell and Tissue Type Transcriptomes

The evolution and diversification of cell types is a key means by which animal complexity evolves. Recently, hierarchical clustering and phylogenetic methods have been applied to RNA-seq data to infer cell type evolutionary history and homology. A major challenge for interpreting this data is that c...

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Detalles Bibliográficos
Autores principales: Liang, Cong, Musser, Jacob M, Cloutier, Alison, Prum, Richard O, Wagner, Günter P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800078/
https://www.ncbi.nlm.nih.gov/pubmed/29373668
http://dx.doi.org/10.1093/gbe/evy016