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Improving validation methods for molecular diagnostics: application of Bland-Altman, Deming and simple linear regression analyses in assay comparison and evaluation for next-generation sequencing

AIMS: A standard approach in test evaluation is to compare results of the assay in validation to results from previously validated methods. For quantitative molecular diagnostic assays, comparison of test values is often performed using simple linear regression and the coefficient of determination (...

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Detalles Bibliográficos
Autores principales: Misyura, Maksym, Sukhai, Mahadeo A, Kulasignam, Vathany, Zhang, Tong, Kamel-Reid, Suzanne, Stockley, Tracy L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800325/
https://www.ncbi.nlm.nih.gov/pubmed/28747393
http://dx.doi.org/10.1136/jclinpath-2017-204520