Monitoring disease progression with plasma creatinine in amyotrophic lateral sclerosis clinical trials

OBJECTIVES: Plasma creatinine is a predictor of survival in amyotrophic lateral sclerosis (ALS). It remains, however, to be established whether it can monitor disease progression and serve as surrogate endpoint in clinical trials. METHODS: We used clinical trial data from three cohorts of clinical t...

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Detalles Bibliográficos
Autores principales: van Eijk, Ruben P A, Eijkemans, Marinus J C, Ferguson, Toby A, Nikolakopoulos, Stavros, Veldink, Jan H, van den Berg, Leonard H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Neuromuscular
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800333/
https://www.ncbi.nlm.nih.gov/pubmed/29084868
http://dx.doi.org/10.1136/jnnp-2017-317077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800333/
https://www.ncbi.nlm.nih.gov/pubmed/29084868
http://dx.doi.org/10.1136/jnnp-2017-317077

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