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Monitoring disease progression with plasma creatinine in amyotrophic lateral sclerosis clinical trials
OBJECTIVES: Plasma creatinine is a predictor of survival in amyotrophic lateral sclerosis (ALS). It remains, however, to be established whether it can monitor disease progression and serve as surrogate endpoint in clinical trials. METHODS: We used clinical trial data from three cohorts of clinical t...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BMJ Publishing Group
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800333/ https://www.ncbi.nlm.nih.gov/pubmed/29084868 http://dx.doi.org/10.1136/jnnp-2017-317077 |