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Histone octamer rearranges to adapt to DNA unwrapping
Nucleosomes, the basic unit of chromatin, package and regulate expression of eukaryotic genomes. Although the structure of the intact nucleosome has been studied, little is known about structures of its partially unwrapped, transient intermediates. In this study, we present 9 cryo EM structures of d...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800490/ https://www.ncbi.nlm.nih.gov/pubmed/29323273 http://dx.doi.org/10.1038/s41594-017-0005-5 |