A mathematical model of multisite phosphorylation of tau protein

Abnormal tau metabolism followed by formation of tau deposits causes a number of neurodegenerative diseases called tauopathies including Alzheimer’s disease. Hyperphosphorylation of tau protein precedes tau aggregation and is a topic of interest for the development of pharmacological interventions t...

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Detalles Bibliográficos
Autores principales: Stepanov, Alexander, Karelina, Tatiana, Markevich, Nikolai, Demin, Oleg, Nicholas, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800643/
https://www.ncbi.nlm.nih.gov/pubmed/29408874
http://dx.doi.org/10.1371/journal.pone.0192519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800643/
https://www.ncbi.nlm.nih.gov/pubmed/29408874
http://dx.doi.org/10.1371/journal.pone.0192519

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