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Chromatin remodeler ALC1 prevents replication-fork collapse by slowing fork progression

ALC1 (amplified in liver cancer 1), an SNF2 superfamily chromatin-remodeling factor also known as CHD1L (chromodomain helicase/ATPase DNA binding protein 1-like), is implicated in base-excision repair, where PARP (Poly(ADP-ribose) polymerase) mediated Poly(ADP-ribose) signaling facilitates the recru...

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Detalles Bibliográficos
Autores principales: Ooka, Masato, Abe, Takuya, Cho, Kosai, Koike, Kaoru, Takeda, Shunichi, Hirota, Kouji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800655/
https://www.ncbi.nlm.nih.gov/pubmed/29408941
http://dx.doi.org/10.1371/journal.pone.0192421