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Splenic macrophages are required for protective innate immunity against West Nile virus

Although the spleen is a major site for West Nile virus (WNV) replication and spread, relatively little is known about which innate cells in the spleen replicate WNV, control viral dissemination, and/or prime innate and adaptive immune responses. Here we tested if splenic macrophages (MΦs) were nece...

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Detalles Bibliográficos
Autores principales: Bryan, Marianne A., Giordano, Daniela, Draves, Kevin E., Green, Richard, Gale, Michael, Clark, Edward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800658/
https://www.ncbi.nlm.nih.gov/pubmed/29408905
http://dx.doi.org/10.1371/journal.pone.0191690