Genome-wide profiling reveals functional diversification of ∆FosB gene targets in the hippocampus of an Alzheimer's disease mouse model

The activity-induced transcription factor ∆FosB has been implicated in Alzheimer’s disease (AD) as a critical regulator of hippocampal function and cognition downstream of seizures and network hyperexcitability. With its long half-life (> 1 week), ∆FosB is well-poised to modulate hippocampal gene...

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Detalles Bibliográficos
Autores principales: You, Jason C., Stephens, Gabriel S., Fu, Chia-Hsuan, Zhang, Xiaohong, Liu, Yin, Chin, Jeannie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800686/
https://www.ncbi.nlm.nih.gov/pubmed/29408867
http://dx.doi.org/10.1371/journal.pone.0192508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800686/
https://www.ncbi.nlm.nih.gov/pubmed/29408867
http://dx.doi.org/10.1371/journal.pone.0192508

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