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MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection

Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel human coronavirus that emerged in 2012, causing severe pneumonia and acute respiratory distress syndrome (ARDS), with a case fatality rate of ~36%. When expressed in isolation, CoV accessory proteins have been shown to interfere with...

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Detalles Bibliográficos
Autores principales: Canton, Javier, Fehr, Anthony R., Fernandez-Delgado, Raúl, Gutierrez-Alvarez, Francisco J., Sanchez-Aparicio, Maria T., García-Sastre, Adolfo, Perlman, Stanley, Enjuanes, Luis, Sola, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800688/
https://www.ncbi.nlm.nih.gov/pubmed/29370303
http://dx.doi.org/10.1371/journal.ppat.1006838