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Sequence-based multiscale modeling for high-throughput chromosome conformation capture (Hi-C) data analysis

In this paper, we introduce sequence-based multiscale modeling for biomolecular data analysis. We employ spectral clustering method in our modeling and reveal the difference between sequence-based global scale clustering and local scale clustering. Essentially, two types of distances, i.e., Euclidea...

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Detalles Bibliográficos
Autor principal: Xia, Kelin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800693/
https://www.ncbi.nlm.nih.gov/pubmed/29408904
http://dx.doi.org/10.1371/journal.pone.0191899