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SUV420H2 is an epigenetic regulator of epithelial/mesenchymal states in pancreatic cancer

Epithelial-to-mesenchymal transition is implicated in metastasis, where carcinoma cells lose sessile epithelial traits and acquire mesenchymal migratory potential. The mesenchymal state is also associated with cancer stem cells and resistance to chemotherapy. It might therefore be therapeutically be...

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Detalles Bibliográficos
Autores principales: Viotti, Manuel, Wilson, Catherine, McCleland, Mark, Koeppen, Hartmut, Haley, Benjamin, Jhunjhunwala, Suchit, Klijn, Christiaan, Modrusan, Zora, Arnott, David, Classon, Marie, Stephan, Jean-Philippe, Mellman, Ira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800801/
https://www.ncbi.nlm.nih.gov/pubmed/29229751
http://dx.doi.org/10.1083/jcb.201705031