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The two TRAPP complexes of metazoans have distinct roles and act on different Rab GTPases

Originally identified in yeast, transport protein particle (TRAPP) complexes are Rab GTPase exchange factors that share a core set of subunits. TRAPPs were initially found to act on Ypt1, the yeast orthologue of Rab1, but recent studies have found that yeast TRAPPII can also activate the Rab11 ortho...

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Detalles Bibliográficos
Autores principales: Riedel, Falko, Galindo, Antonio, Muschalik, Nadine, Munro, Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800803/
https://www.ncbi.nlm.nih.gov/pubmed/29273580
http://dx.doi.org/10.1083/jcb.201705068