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Srf controls satellite cell fusion through the maintenance of actin architecture

Satellite cells (SCs) are adult muscle stem cells that are mobilized when muscle homeostasis is perturbed. Here, we show that serum response factor (Srf) is needed for optimal SC-mediated hypertrophic growth. We identified Srf as a master regulator of SC fusion required in both fusion partners, wher...

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Detalles Bibliográficos
Autores principales: Randrianarison-Huetz, Voahangy, Papaefthymiou, Aikaterini, Herledan, Gaëlle, Noviello, Chiara, Faradova, Ulduz, Collard, Laura, Pincini, Alessandra, Schol, Emilie, Decaux, Jean François, Maire, Pascal, Vassilopoulos, Stéphane, Sotiropoulos, Athanassia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800804/
https://www.ncbi.nlm.nih.gov/pubmed/29269426
http://dx.doi.org/10.1083/jcb.201705130