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WASP family proteins and formins compete in pseudopod- and bleb-based migration

Actin pseudopods induced by SCAR/WAVE drive normal migration and chemotaxis in eukaryotic cells. Cells can also migrate using blebs, in which the edge is driven forward by hydrostatic pressure instead of actin. In Dictyostelium discoideum, loss of SCAR is compensated by WASP moving to the leading ed...

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Detalles Bibliográficos
Autores principales: Davidson, Andrew J., Amato, Clelia, Thomason, Peter A., Insall, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800805/
https://www.ncbi.nlm.nih.gov/pubmed/29191847
http://dx.doi.org/10.1083/jcb.201705160